HK researchers develop microrobots to enhance C. difficile toplastic bands braceletsxin detection

Must See Denver Concerts And Music Festivals The bottom line is this: No one has made a wristband that the "bad guys" cannot beat. But by using wristbands, we just make their lives a little more difficult. SET THE DATE: The date of your event will depend on a couple of things. If it is a birthday or anniversary event wristbands then you are controlled by the date. If it is just a party the date may be controlled by the locations availability. If the event is at your home then you are in control. Pick what ever date you want. I have even gone as far as check with some guests a couple weeks in advance to make sure they are available on a certain date. I really like success! Shorts: Rated PGfor mild action and some rude humor. A rainbow-colored rock has the power to grant wishes. As the rock changes hands among the children, the world turns upside down as crocodile armies and spaceships begin to appear. Once the adults get involved, things get really out of whack. Starring Jon Cryer sport wristbands William H. Macy, Leslie Mann and James Spader. Shows cost anywhere for $5 to $12, depending on whether an out-of-town group is playing, how popular the bands are, etc. If it"s a pretty big show, you can save a couple bucks by purchasing tickets online in advance. Some of the shows are all ages but, unfortunately, quite a few require attendees to be at least 21 years old. You can check their online calendar for specifics. Every year groups of musicians band together to tour the states. After the success of the CMA Country festival wristbands in 2009, the summer of 2010 burst open with more energy and even more diverse acts. Nearly every major city hosted a tour and not a single one lacked the full octane buzz that Country offers. Since "91 the Chicago Country festival wristbands at Soldier Field has been the ripest environment for newcomers to the genre. Chicago mayor Richard Daley confessed he had a weak spot for the slide guitar with the moaning pitch of steel on steel. The first year of the festival, 42,000 fans supported his love and ever since, it has been one of the biggest summer events for the genre. Add music. There are times when the sounds of nature are perfect to accompany your exercise. Then, there are the times when your soul feels the need to bust a move! The right music at the right time can be all the motivation you need to keep going. Go on, shake your groove thing! It"s good for you. It"s "everyday guy and gal"s golf tournament," where competitors find out what it feels like to play in a professional tour tournament. And once you"ve tried it, you tend to return year after year.
[Photo/cuhk.edu.hk]

HONG KONG -- The Chinese University of Hong Kong said on Wednesday that its research team has recently developed microrobots that can detect Clostridium difficile bacterial toxins accurately within 15 minutes.

Clostridium difficile, aka C. difficile, is the most common hospital acquired enteric infection. The toxins secreted by C. difficile will cause diarrhea, fever and hematochezia. In some cases, patients may develop life-threatening peritonitis and sepsis.

Currently, the stool samples of hospitalized patients with diarrhea are being tested in the laboratory to determine the presence of C. difficile. The process normally takes one to two days.

The research team led by Li Zhang, associate professor of the university"s Department of Mechanical and Automation Engineering, has developed fluorescent magnetic spore-based microrobots to shorten the detection time. These devices carry functionalized carbon dots that emit fluorescence, the intensity of which will gradually decrease during "on-the-fly" reaction with C. difficile toxins.

Furthermore, the unique and intricate three-dimensional architecture of the microrobots enables easy spreading and swarming in diluted stool samples. Such a continuous and efficient movement acts as active searching, thus facilitating higher detection efficiency and sensitivity than static counterparts.

This enables the reaction even if the sample has a low concentration of toxins. Also, when applying an external magnetic field, the microrobots can perform a controllable movement in the stool samples and be tracked with automation in an easy manner.

Zhang said that in the experiment, all the microrobots placed into stool samples infected by C. difficile no longer emit fluorescence in 15 minutes. This new motion-based detection technique provides a promising solution to the rapid clinical sensing to supplement, or potentially replace the current detection methods in clinic.

"This new technology eventually provides opportunities to develop a multiplex new quick-sensing system not only for C. difficile toxins, but also for many bioanalytical fields including food, chemicals and early diagnosis of other bacteria-infected diseases, " Zhang said, adding that the team will construct an automated microrobotic platform for practical diagnostic application that can be used in clinics and hospitals.

The finding has been published in Science Advances, a scientific journal of the American Association for the Advancement of Science.